Thursday, November 15, 2012

Six Monmouth College football players All-MWC

Six Monmouth College football players have earned all-conference honors in a vote of the Midwest Conference coaches.

Junior offensive lineman A.J. Ulrich and sophomore place kicker Ace Henricks earned their first league honors after being named to the first team offense.

Junior punter Brik Wedekind? earned his third all-MWC honor with his selection to the first team defense.

Record-setting junior running back Trey Yocum was honored for the second time with his inclusion on the second team offense. Second team defensive honors went to senior defensive lineman Sam Hoster, who earned his first all-league award.

Senior offensive lineman Todd Groth was named an all-conference performer for the second time, making the honorable mention squad.

Yocum, a Bushnell product, became only the second Monmouth back in school history to gain more than 1,000 yards in two separate seasons. Averaging more than five yards per carry, he picked up 1,166 rushing yards to move to third all-time with 2,983 yards. With a year left in his career, Yocum set the TD record, scoring 13 this season to set the new career mark at 45.
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Source: http://www.galesburg.com/x1582303658/Six-Monmouth-College-football-players-All-MWC

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Tuesday, November 13, 2012

'Dancing' judges melt down over Shawn's samba

ABC

Judges Carrie Ann Inaba and Len Goodman argue after Shawn Johnson's samba.

By Ree Hines, TODAY contributor

Honoring the military was the official post-Veterans Day theme for week-eight of "Dancing With the Stars: All-Stars," but the unofficial theme was war -- as in big ballroom battles among the judges.

The biggest fray of the night by far happened when all-star leading lady Shawn Johnson hit the floor. Actually, her first dance of the night -- a tearjerker of a Viennese waltz that earned her 29.5 points -- went over well with head judge Len Goodman and his peers on the panel. But when she returned for her trio routine, it was nothing but tribal trouble.

That's because the dance she performed alongside pros Derek Hough and Mark Ballas was meant to be a samba. But the high-energy, crowd-pleasing number felt more like a tribal-tribute freestyle -- a very well performed, fun freestyle, but an only slightly samba-infused one.

"Listen, if I was sitting in the audience I'd be cheering along," Len admitted after the standing-O crowd had barely returned to their seats.

But he wasn't cheering -- he was judging a samba with "very little content." So little, that he warned Shawn the dance could spell the end of her dancing days.

"If you go home tomorrow, don't blame me!" he said. Then, motioning to her pro partners, he added, "Blame those two."

Bruno Tonioli applauded the art of the dance, but he had to give Len his due on the critique. Carrie Ann Inaba? Not so much. She disagreed with both of her fellow panelists and let them know it.

"You can't disagree with the truth," Len shot back.

What happened next was a rare moment of ballroom breakdown. Len and Carrie Ann stood up and faced off, shouting over one another and turning the spotlight on themselves. (Though a crouching, arm-pumping Mark vied for his own moment during the melee.)

The judges eventually calmed down enough to deliver their divergent scores, which ranged from a high of 10 (from Carrie Ann) to a low of 7 (from guess who).

But that was far from the only fracas of the night.

When Kelly Monaco performed a spin-filled Viennese waltz packed with strong lines and smooth transitions, the panelists started at it.

Len enjoyed the flow, but felt the movement was too sharp, and when Carrie Ann attempted to school him otherwise, he went for the metaphorical jugular.

"I have my standards," he snipped. "She has none!"

Ouch.

Bruno advised Kelly to ignore the resident grump, and Carrie chose too ignore him too. Instead she just raved over the routine.

Despite all of the hubbub, Len was only a half-point behind his fellow judges when he presented his 9 paddle. And later they all agreed that Kelly's jive trio, along with regular partner Val Chmerkovskiy and returning pro Louis Van Amstel, was worthy of a matching set of 9.5s.

Even Gilles Marini even saw a disagreement following his quickstep. Bruno and Len were convinced the dance was flawless, but Carrie Ann felt certain she spotted a few "wobbles." While Bruno protested, the group didn't let it cause much of a commotion. Instead, the guys gave out perfect scores and Carrie Ann held back a (wobbly) half-point.

Meanwhile Gilles witnessed another mild disparity when he returned for his trio salsa (with Peta Murgatroyd and Chelsie Hightower). According to Carrie Ann, his musicality was off. According to Bruno, he lost timing. But Len, with his 10 paddle at the ready again, thought Gilles was just perfect.

Of course, the esteemed experts found a few things they could agree on. Apolo Anton Ohno's two routines -- a tango and a jive -- were marked good efforts. Kirstie Alley's Viennese Waltz was low on content but well finessed, and her paso doble was packed with content, but it wasn't good content.

And when it came to Melissa Rycroft's quickstep and paso doble, they were so in-tuned to each other that Len, Bruno and Carrie Ann presented unified 10s.

As for Emmitt Smith, the judges got along fine after his steps too. Heck. Despite a visible fumble in his Viennese waltz, they only knocked off one point between them. But they sure gave fans of ballroom dance something to argue about when they scored the hall of famer's trio salsa (with Cheryl Burke and Kym Johnson).

The dance was light on moves, contained sloppy lines and lacked standout moments. And yet somehow Len and the gang saw fit to give it a perfect 30.

Talk about something worth getting upset about!

Who do you think put on the very best performance Monday night? Take our poll below and then share your thoughts about the judges' scoring on our Facebook page. And be sure to join us on Tuesday at 12:30 p.m. PT / 3:30 ET to chat about who you think might be going home!

Source: http://theclicker.today.com/_news/2012/11/12/15120419-dancing-with-the-stars-judges-melt-down-over-shawn-johnsons-tribal-trio?lite

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A sip of resveratrol and a full p53: Ingredients for a successful cell death

A sip of resveratrol and a full p53: Ingredients for a successful cell death [ Back to EurekAlert! ] Public release date: 13-Nov-2012
[ | E-mail | Share Share ]

Contact: Jerson Lima Silva
jerson@bioqmed.ufrj.br
55-212-562-6756
Publicase Comunicao Cientfica

Resveratrol anti-tumor properties are rescued through p53 transfection in p53 defective cancer cell lines

Rio de Janeiro, Brazil- Resveratrol is a naturally occurring dietary compound found in grapes, berries, and peanuts. This polyphenol protects plants against pathogens such as bacteria and fungi by inducing cell death in invading organisms. The compound was discovered in red wine in 1939 but by large did not attract the attention of the scientific community. More recently, pre-clinical studies have revealed the many beneficial properties of resveratrol. These include antidiabetic, cardioprotective, and chemopreventive effects. The latter has been associated to resveratrol antioxidant and anti-inflammatory proprieties.

A number of studies show that resveratrol induces cell death in different types of cancers, both in humans and animal models. However, the potential anti-tumor effect of resveratrol is still little understood as the compound seems to induce cell death in a number of cancer cells whereas in others no effect is observed, even when massive doses of resveratrol are used. A phase I study on the pharmacokinetic properties of resveratrol as a potential cancer chemopreventive agent has concluded that consumption of high levels of resveratrol would be insufficient to provide the amounts of resveratrol needed to elicit its chemopreventive proprieties. Nevertheless, a few ongoing clinical trials investigate the effects of resveratrol on a number of diseases, including colon cancer.

More recently, the anti-tumor functions of resveratrol have been associated to p53, a protein responsible for suppressing tumor development in the body. p53 is one of the main blockers of the cell cycle, leading cells to the death row. A faulty p53 is unable to suppress cell growth, which ultimately results in tumor development. Indeed, studies have shown that p53 is either defective or simply absent in most cancers.

To investigate whether resveratrol anti-tumor effects, as observed in some cancer cell lines, depend on the status of the cell's p53 gene, a group led by Dr Jerson L. Silva at the Universidade Federal do Rio de Janeiro, Brazil, tested the effects of resveratrol in H1299, a human non-small lung carcinoma cell line carrying only a partial fragment of the p53 gene and compared the results with MCF-7, A549, and H460, which are cancer cell lines carrying normal copies of p53. The study shows that although resveratrol affects the viability of all cancer cell lines, MCF-7, A549, and H460 are more sensitive to the effects of resveratrol than H1299. While MCF-7 cell lines die after exposure to resveratrol, H1299 remains resistant. Additional findings indicate that the toxic effect of resveratrol on MCF-7, A549, and H460 cell lines is mediated by p53.

The research group then went one step further and asked what would happen if a normal copy of p53 is added to the previously p53-defective H1299 cancer cell line. The results, published this week in PLOS ONE, show that introduction of a normal copy of p53 in H1299 turns the cell line sensitive to the anti-tumor effects of resveratrol, similarly to that observed in other cancer cell lines (MCF-7, A549, and H460). "Our findings may have potential applications in cancer cell lines that are under p53 control," says Dr Danielly Ferraz da Costa, the first author of the study. "Also, the introduction of the p53 gene in p53-defective tumors, followed by resveratrol treatment, may represent a novel and promising therapeutic approach in our fight against cancer," says the young author.

###

The article entitled "Transient transfection of wild-type p53 gene triggers resveratrol-induced apoptosis in cancer cells" is available at http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0048746

The study was funded by the National Council for Scientific and Technological Development (CNPq), the Rio de Janeiro State Foundation for Research (FAPERJ), the Ministry of Health (MS/Decit), Cancer Foundation, and the National Institute of Science and Technology for Structural Biology and Bioimaging (INBEB).


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


A sip of resveratrol and a full p53: Ingredients for a successful cell death [ Back to EurekAlert! ] Public release date: 13-Nov-2012
[ | E-mail | Share Share ]

Contact: Jerson Lima Silva
jerson@bioqmed.ufrj.br
55-212-562-6756
Publicase Comunicao Cientfica

Resveratrol anti-tumor properties are rescued through p53 transfection in p53 defective cancer cell lines

Rio de Janeiro, Brazil- Resveratrol is a naturally occurring dietary compound found in grapes, berries, and peanuts. This polyphenol protects plants against pathogens such as bacteria and fungi by inducing cell death in invading organisms. The compound was discovered in red wine in 1939 but by large did not attract the attention of the scientific community. More recently, pre-clinical studies have revealed the many beneficial properties of resveratrol. These include antidiabetic, cardioprotective, and chemopreventive effects. The latter has been associated to resveratrol antioxidant and anti-inflammatory proprieties.

A number of studies show that resveratrol induces cell death in different types of cancers, both in humans and animal models. However, the potential anti-tumor effect of resveratrol is still little understood as the compound seems to induce cell death in a number of cancer cells whereas in others no effect is observed, even when massive doses of resveratrol are used. A phase I study on the pharmacokinetic properties of resveratrol as a potential cancer chemopreventive agent has concluded that consumption of high levels of resveratrol would be insufficient to provide the amounts of resveratrol needed to elicit its chemopreventive proprieties. Nevertheless, a few ongoing clinical trials investigate the effects of resveratrol on a number of diseases, including colon cancer.

More recently, the anti-tumor functions of resveratrol have been associated to p53, a protein responsible for suppressing tumor development in the body. p53 is one of the main blockers of the cell cycle, leading cells to the death row. A faulty p53 is unable to suppress cell growth, which ultimately results in tumor development. Indeed, studies have shown that p53 is either defective or simply absent in most cancers.

To investigate whether resveratrol anti-tumor effects, as observed in some cancer cell lines, depend on the status of the cell's p53 gene, a group led by Dr Jerson L. Silva at the Universidade Federal do Rio de Janeiro, Brazil, tested the effects of resveratrol in H1299, a human non-small lung carcinoma cell line carrying only a partial fragment of the p53 gene and compared the results with MCF-7, A549, and H460, which are cancer cell lines carrying normal copies of p53. The study shows that although resveratrol affects the viability of all cancer cell lines, MCF-7, A549, and H460 are more sensitive to the effects of resveratrol than H1299. While MCF-7 cell lines die after exposure to resveratrol, H1299 remains resistant. Additional findings indicate that the toxic effect of resveratrol on MCF-7, A549, and H460 cell lines is mediated by p53.

The research group then went one step further and asked what would happen if a normal copy of p53 is added to the previously p53-defective H1299 cancer cell line. The results, published this week in PLOS ONE, show that introduction of a normal copy of p53 in H1299 turns the cell line sensitive to the anti-tumor effects of resveratrol, similarly to that observed in other cancer cell lines (MCF-7, A549, and H460). "Our findings may have potential applications in cancer cell lines that are under p53 control," says Dr Danielly Ferraz da Costa, the first author of the study. "Also, the introduction of the p53 gene in p53-defective tumors, followed by resveratrol treatment, may represent a novel and promising therapeutic approach in our fight against cancer," says the young author.

###

The article entitled "Transient transfection of wild-type p53 gene triggers resveratrol-induced apoptosis in cancer cells" is available at http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0048746

The study was funded by the National Council for Scientific and Technological Development (CNPq), the Rio de Janeiro State Foundation for Research (FAPERJ), the Ministry of Health (MS/Decit), Cancer Foundation, and the National Institute of Science and Technology for Structural Biology and Bioimaging (INBEB).


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-11/pcc-aso111312.php

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Sunday, November 11, 2012 Committed and Blessed |

Sunday, November 11, 2012 Committed and Blessed
Stewardship Series 2 Corinthians 9:6-10 Those who chose to commit themselves will be blessed by the return they receive.
Veteran?s Day Matthew 6:19-24 What you choose as being your treasure will determine your relationships.
Sermon: ?Committed and Blessed?
Theme: As we commit ourselves to Christ in how we use our money we are blessed to be in a relationship that gives all our life value and meaning.
Purpose: The congregation will celebrate the commitment they make to serve Christ and to use their gifts to the glory of God.
Stewardship Dedication Sunday

Questions: What difference does it make if we are committed to Christ? If we are committed to the church? If we are committed to our own values? What does it mean that where your treasure is, there your heart will be also? What has money got to do with faith? What does money have to do with faithfulness? How does our relationship with our money affect our relationships with family, friends, and our happiness?

Message from November 11th 2012?- Click here to listen to the message

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Source: http://www.fdlpresbyterian.org/2012/11/11/sunday-november-11-2012-committed-and-blessed/

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Monday, November 12, 2012

Natural Disasters May Disrupt Mortgage Closings

When Hurricane Sandy smashed into the New York/New Jersey coastline, home buyers in mid-mortgage closing were caught off guard, some going to great lengths to hang onto properties that even surprised some lenders.

The New York Times spoke to Denise Walsh, a partner in Gigliotti & Walsh Fine Properties who said that she had to figure out how to respond to one buyer who chartered a boat to check out his property post Sandy.

?Don?t you know the buyer got a boat, rowed by the house that he?s negotiating and took photos,? she said. ?He e-mailed me photos of the property and said: ?Good news! I?m still interested. But what do we do about this?? So now the negotiation is going to take a different turn.?

In this case, a new appraisal is in order to ensure the home did not sustain serious damage, however every scenario is different making both new home purchases and refinances a red tape nightmare for lenders.

For homes in the middle of mortgage financing post storm, nothing is cut and dry. ?If you are in a FEMA-declared disaster area or emergency area, banks are requiring an inspection of the home to affirm whether there was damage done,? Jason Auerbach, a divisional manager for First Choice Loan Services, told The New York Times. ?They are re-inspecting properties to make sure it?s still a functional property that can be lived in.?

Home re-inspections can range from a simple drive-by appraisal to an in-depth inspection depending upon storm location and overall impact.

?What we don?t want to have the day of the closing is that they go into the property and see evidence of flood damage,? said real estate attorney, Scott Penner. ?Then they?ll want to negotiate at that time, and it creates all sorts of problems.?

Borrowers Try To Ensure Their Rate Lock In

When the storm hit, mortgage rates were at some of the lowest levels since the 1950?s. Bankrate.com?s October 31, 2012 survey had rates at 3.57% for a 30 year fixed rate loan and 2.89% for a 15 year fixed product.

Experts say that borrowers in the path of Sandy during mid-closing should talk to their lender as soon as possible to determine if they can still lock in. According to Neil Garfinkel, a New York City real estate attorney, lenders are typically willing to work with the borrower and extend the rate.

If the home is under contract for purchase and not refinance, borrowers may have issues closing on their home in storm impacted areas, even if their home had not sustained any damage. Garfinkel tells Fox Business News that, ?A buyer who is under contract to buy a house that has been damaged by the hurricane can likely walk from the deal if the home can't be repaired by the closing date. It depends on how the contract was written and how badly the property was damaged.?

Lender Doug Harris offers tips every homeowner and potential homeowner should consider when trying to finance their home:

  • Anticipate closing delay. If the storm hits before you can lock-in at the desired rate and the rate lock expires, ask your lender to honor the original, agreed upon rate--many lenders will help.
  • Be prepared for another inspection. At the very least an exterior inspection may be required for a property located in any area declared a disaster by FEMA.
  • Before you buy, ask for another inspection if your home is located near or within the storm path. Even if your potential home isn?t in the specified FEMA disaster area, consider having it re-inspected to insure no hidden damages are lurking that could cause problems for you post closing.
  • Decide who is responsible for paying for repairs before purchasing a home. If you are about to buy a new home that has been damaged by the storm, come to an agreement about who (buyer or seller) is responsible for making the repairs.
  • For minor damage, ask the seller if they could provide you with a credit for repairs or set up an escrow account with the necessary amount dedicated for repairs.

Credit Unions Take an Extra Step to Ease Loan Pain

In addition to working with borrowers to ensure mortgage closings go off without a hitch; credit unions are going the extra mile to relieve any additional burden for its members.

For homes that sustained damage from the hurricane, Jersey Shore Federal Credit Union ($117 million, Northfield, NJ) has created a low rate loan to help members repair homes from flood damage, remove fallen trees on the property or use it for any recovery reason.

NEFCU ($1.9 billion, Westbury, NY) is also offering a hurricane relief loan, a 1% discount on auto loans, a 90 day auto loan payment deferral and a 0% rate on credit card for home improvement purchases.

Other credit unions offering loan assistance include:

As credit unions band together to aid their members, Mother Nature threw another curve ball at the region--a nor?easter last week.

The New Jersey Credit Union League issued a press release following the storm. "Just when we were starting to see many more New Jerseyans have their power turned back on, we unfortunately were hit with a snowfall that is delaying power restoration and has taken many areas backwards because of downed trees and lines from the snow," said NJCUL President/CEO Paul Gentile. "I want to thank credit unions, leagues and system players from around the country who have stepped up and donated to the National Credit Union Foundation's CU Aid. The funds are needed and appreciated. We will never forget the outpouring of support."

Not sure how to proceed with your loan closing or if you need a home repair loan? Contact your credit union for immediate assistance.

Source: http://www.creditunionsonline.com/news/2012/natural-disasters-may-disrupt-mortgage-closings.html

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